Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-

Name	IWP-2
Synonyms	IWP-2 IWP 2 Wnt Antagonist II, IWP-2 N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide N-(6-methylbenzo[d]thiazol-2-yl)-2-((4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]- IWP 2 N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2d]pyrimidin-2-yl)thio]acetamide
CAS	686770-61-6
InChIKey	WRKPZSMRWPJJDH-UHFFFAOYSA-N

Molecular Formula	C22H18N4O2S3
Molar Mass	466.6
Density	1.52±0.1 g/cm3(Predicted)
Melting Point	257 °C(dec.)
Solubility	DMSO: >5mg/mL
Appearance	powder
Color	Beige
pKa	9.01±0.70(Predicted)
Storage Condition	room temp
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
MDL	MFCD04457599
Use	IWP-2
In vitro study	IWP-2 are very effective in both regenerative medicine and anti-cancer. IWP-2 inactivate Porcn, a membrane that binds to O-acyltransferase (MBOAT) and selectively inhibits Wnt palmitoylation. IWP-2 inhibits Wnt-dependent phosphorylation of Lrp6 receptor and Dvl2, and also inhibits β-catenin accumulation.

WGK Germany

Last Update：2024-01-02 23:10:35

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Product Name: IWP-2 Visit Supplier Webpage Request for quotation
CAS: 686770-61-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]- Request for Quotation